7-(3-Nitrophenyl)-9,10-dihydro-7H-benzo[h]cyclopenta[b]quinolin-8(11H)-one

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7-(3-Nitro­phen­yl)-9,10-dihydro-7H-benzo[h]cyclo­penta­[b]quinolin-8(11H)-one

In the title compound, C(22)H(16)N(2)O(3), the naphthalene ring, the 1,4-dihydro-pyridine ring and the cyclo-pent-2-enone ring are nearly coplanar, with the dihedral angles between the neighbouring rings being 1.93 (11) and 2.30 (9)°, respectively. The benzene ring group at position 7 and the 1,4-dihydro-pyridine ring form a dihedral angle of 78.75 (4)°. Inter-molecular N-H⋯O hydrogen bonds and...

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Oxidative Aromatization, Cytotoxic Activity Evaluation and Conformational Study of Novel 7-aryl-10, 11-dihydro-7H-chromeno [4, 3-b]quinoline-6, 8(9H, 12H)-dione derivatives

In the present work, novel 7-aryl-10, 11-dihydro-7H-chromeno [4, 3-b]quinoline-6, 8(9H, 12H)-dione derivatives were synthesized by oxidation of 7-aryl-8, 9, 10, 12-tetrahydro-7H-chromeno[4, 3-b]quinoline-6, 8-diones in the presence of silica sulfuric acid/NaNO2 with yields of 64-74%. Cytotoxic activity of synthesized compounds was assessed on three different human cancer cell lines (K562, LS180...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2011

ISSN: 1600-5368

DOI: 10.1107/s1600536811043546